Sentence examples for underlying the establishment of from inspiring English sources

Two body size clines were rapidly established in the two continents, but the cellular mechanism underlying the establishment of the clines is not the same: the North American cline is based on cell area differences, the South American cline on cell number differences.

The molecular mechanisms underlying the establishment of immune tolerance by this DC population are poorly understood, and the methods by which developing cancers can co-opt this pathway to subvert immune surveillance are currently unknown.

The mechanism underlying the establishment of CNV mosaicism during mitosis remains unclear.

At present, we cannot precisely describe the exact mechanism underlying the establishment of differentiated cell lines from ES cells.

Those molecular changes which occurred much more rapidly between 2 and 48 h are crucial for identifying novel genes underlying the establishment of dominance and associated changes in behaviour and physiology.

The mechanisms underlying the establishment of aberrant DNA methylation patterns are still largely unknown.

In this Review, we discuss studies revealing the epigenetic mechanisms, as well as the post-transcriptional and post-translational modifications by chromatin modifiers, that underlie the establishment of these signalling networks and the rapid induction of innate immune molecules during infection.

Patterns of methylation at lysine 4 and 27 of histone H3 have been associated with states of gene activation and repression that are developmentally regulated and are thought to underlie the establishment of lineage specific gene expression programs.

This review discusses current understanding of the pathophysiologic mechanisms that underlie the establishment of bone metastasis and potential molecular therapeutic strategies for prevention and treatment of bone metastasis.

Model studies in the early eighties have shown that a unidirectional transport mechanism could underlie the establishment of auxin maxima [ 59, 68].

There is a growing consensus that complex co-adaptation between the persistent parasite infection and the balanced host immune response underlies the establishment of Indeterminate clinical form of Chagas disease.