GTR1 cells [9], [11], a derivative of R1 ES cells bearing the puromycin-resistance gene driven by the cardiomyocyte-specific α-myosin heavy chain promoter, were used as an in vitro model of cardiogenesis to elucidate whether a recruitment of Smad signaling may be a mechanism underlying the cardiogenic commitment induced by HBR.
Here we dissect the events underlying the progressive commitment of pluripotent EpiSCs to PS-derived lineages.
Of course, this treatment does not do justice to some of the intuitions underlying the prima facie commitments to events for instance, events can be perceived but times cannot [Gibson 1975].
The LoA underlies the parties' commitment to support, strengthen and fast track the implementation of sustainable solutions to urban water supply in the towns of Boroma, Erigavo, Tog Wajaale and Burao.
A central commitment underlying the project was to design a curriculum that could address social inequalities in Papua, specifically the significant under-representation of Papuan native peoples in the entrepreneurship sector.
However, the molecular mechanism underlying the substrate-dependent osteogenic commitment of these cells remains unclear.
In order to fulfill the therapeutic potential of human ESCs (hESCs) and iPSCs, an understanding of the fundamental molecular properties underlying the nature of pluripotency and commitment is required, along with the development of methods for assessing biological equivalency among different cell populations.
The networks differ in their potential to generate efficiency and legitimacy gains from collaboration, their commitment to the ideals underlying the institutional mandate, and their willingness to pursue effective collaboration in light of the influence of other external constituents.
Underlying the fear described above was mistrust associated with perceived lack of government's commitment to instil transparency and good governance.
Underlying the government's vigorous lobbying is a debate about whether Switzerland will remain neutral and isolationist or move, as most government ministers prefer, into the broader European community, with the defense commitments that would entail.
