Sentence examples for underlying the activation of from inspiring English sources
To develop therapies that can reduce PMN-induced tissue damage, it is crucial to elucidate the mechanisms underlying the activation of PMNs.
The findings of the present study not only pave way for an in-depth investigation of the molecular mechanism(s) underlying the activation of FGF signaling but also provide avenues for the rational design of potent inhibitors against FGF-mediated pathogenesis.
However, to date, the mechanisms underlying the activation of ADAMs are unknown.
Molecular pathways underlying the activation of dendritic cells (DCs) in response to Herpes Simplex Virus type 1 (HSV-1) are poorly understood.
Thus, aromatase has emerged as a potential factor contributing to brain sex differences underlying the activation of male-typical sexual behavior.
Our results suggest that the mechanism underlying the activation of the APC/CCdc20 upon mitotic inhibition of transcription or translation involves cyclin B1 gene expression.
The signaling mechanisms that underlie the activation of the mitogenic ERK growth response by the GHS-R1a are complex and result from both classical G protein-regulated effectors and β-arrestin dependent ERK recruitment [6].
Distinct mechanisms underlie the activation of coagulation and the inhibition of fibrinolysis as the activation of coagulation required the generation of IL-6, whereas the increase in PAI-1 required signaling through TNF-α independent of IL-6.
This does not eliminate the possibility that second messenger pathways directly coupled to the CaR could underlie the activation of PTHrP expression in the HARA line.
This is surprising considering the interaction of PC1 (overexpressed C-terminal cytoplasmic tail) with TSC2 that was hypothesized to underlie the activation of mTOR observed in renal cystic epithelial cells from patients with ADPKD (34– 34).
A deeper understanding of the genes underlying the activation or depression of the different T helper subsets responses is considered of great significance for resistance and tolerance of livestock species [ 64].
