That's energising in itself, and then you start to pick up on the complexity of the script, all the underlying strands that are threaded through the play in such a subtle, revealing way".
The observed TA and GC skews in the flanking regions of human ORIs imply that there are underlying strand-specific substitution patterns that are coupled to replication in the human genome.
In conclusion, analyzing sequence features underlying miRNA strand selection bias in humans and flies, we find several outstanding features characterising human, but not fly miRNAs.
Very strong protection against exchange with solvent deuterium in the native state was found in a subset of buried positions in α-helices and pervasively in the underlying β-strands associated with a pair of large clusters of isoleucine, leucine and valine (ILV) side chains located in the α781 2 and α23 6β7 segments of the 8 barrel.
"This is part of an underlying animistic magical strand of thinking that does see success in the world as due to the basic spiritual powers that run it," said Paul Stange, an American who is an expert on Indonesian mysticism at Murdoch University in Australia.
Whatever the underlying cause, these strand-specific mutational biases in the mitochondrial genome undoubtedly generate increased mutational load and nonoptimal codon usage.
This result is biologically surprising and the mechanism underlying this difference in strand bias between exons and introns is currently unknown.
In this section, we do not focus on the underlying mechanism of the strand mutation biases, which lead to the compositional asymmetry in turn.
We compared the alignment characteristics of full 2D sequences, as well their underlying template and complementary strand sequences, using the LAST aligner with two different parameter settings (see Methods).
A multi-factorial cause underlying this sperm whales' mass stranding is proposed herein based upon the results of postmortem investigations as well as of the detailed analyses of the geographical and historical background.
