Sentence examples for underlying regulation from inspiring English sources

Given the evidence that TFEB can be acetylated at K116 site and the knowledge that acetylation status is regarded as a critical mechanism underlying regulation of activities of numerous transcription factors, we intended to identify the upstream regulator that targets TFEB.

A molecular understanding of processes underlying regulation and adaptation of bacterial physiology may provide novel avenues for the development of antibiotics with unconventional modes of action.

We use biophysical methods such as control of second messengers by photolysis of light sensitive caged compounds, measurement of second messengers with fluorescent dyes, tracking of vesicle movements with vital vesicle membrane labeling dyes, and computational modeling, as well as electrophysiological techniques, to study the mechanisms underlying regulation of synaptic transmission.

After reviewing the policy justifications underlying regulation across the financial services industry, the Essay summarizes the distinctive regulatory structures that characterize U.S. oversight of each major sector of the industry: private contract, securities regulation, futures contracts, investment companies, depository institutions, insurance companies, and employee benefit plans.

Dr. Norbert de Bruijn excelled not only in perioperative TEE, but also in operating room management. of mechanisms underlying regulation of adrenergic receptors in health and disease.

In summary, we identify protein acetylation as a novel mechanism underlying regulation of TFEB transcriptional activity for the first time, and demonstrate that deacetylation of TFEB in microglia enhances lysosomal biogenesis by stimulating expression of its target genes, which ultimately facilitates fAβ degradation and decreased amyloid plaque deposition.

Finally, we report many changes in phosphorylation of proteins implicated in cytoskeletal and mitotic spindle dynamics that may underlie regulation of cell cycle and morphogenesis.

In a broader sense, even robust molecular biomarkers would underlie regulation networks, which would render extrapolation of effects over time difficult.

Child maltreatment and neural systems underlying emotion regulation.

Mechanisms Underlying Emotion Regulation and Developmental Psychopathology (2017).

Functions and mechanisms underlying this regulation are barely understood.