The link between size and topological characteristics of networks underlying range-limiting traits in various species could be tested in a straightforward, if correlational, manner.
Ideally, a satisfying answer to these questions would include both an analysis of what social conventions are and a description of the particular conventions underlying some range of "conventional" facts.
The advent of genetic tools such as RNAi [17] has enabled researchers to identify the genetic mechanisms underlying a range of physiological traits, including egg-production and sexual receptivity in Drosophila [e.g., 14].
Excitotoxicity, due to excessive and deleterious calcium influx into cells, has long been recognised as a common mechanism underlying the range of neurodegenerative diseases including Alzheimer's, Parkinson's and Motor Neuron diseases [1] [4].
The further characterisation of genes involved in copper homeostasis is therefore required to provide additional candidate genes and support our understanding of the mechanisms underlying a range of copper-related diseases [2].
This multi-dimensional approach is also revealing a number of common mutational signatures, providing insight into the complex mechanisms underlying a range of cancer types [ 29, 30].
Research is now at a point where IU is postulated to be a transdiagnostic maintaining factor underlying a range of psychological disorders (McEvoy and Mahoney, 2011a, 2011b).
Its strength lies in the depth of its enquiry and its ability to capture the complexity of the evidence base and value judgements underlying the range of different views.
We have used such approaches to find novel inhibitors of the important cAMP hydrolyzing phosphodiesterase 4 (PDenzymezyme family, which has been implicated in the pathophysiology underlying a range of diseases and conditions that include schizophrenia, stroke and asthma [6].
We further illustrated the utility of the GSCA tool to unravel potential regulatory mechanisms underlying a range of leukemia gene sets, thus suggesting potential future application of GSCA to build hypotheses to investigate transcriptional control mechanisms responsible for the expression of gene sets with diagnostic, prognostic, or therapeutic relevance.
The underlying aetiology ranges from congenital lesions to infective and inflammatory conditions, and various other benign or malignant masses [1].
