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The reduced model was used to investigate the effect of changes to the underlying parameters for the genotype interaction; viz.
When an analytical approach is applicable this data takes the form of operating equations that relate the underlying parameters; for the numerical approach operating data are presented graphically.
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There are many ways we could allow the unknown events to influence our estimates of the underlying parameters for each process.
In the case of the cellular function filter, we have used the distance as the underlying parameter for plotting the ROC curve (Figure 1A).
We define a new protocol for deducing the underlying parameters of the electrochemical system, such as bulk concentrations, diffusion coefficients, the half-wave potential, and the double-layer capacitance (if it is linear), from the amplitudes and phases of the different harmonics, and the dc part of the current response.
Finally, we performed the global sensitivity analysis of the underlying parameters to find the key network wirings responsible for the stability of the oscillation system.
For each of them, we re-estimated the underlying parameters using the same ABC procedure used for our empirical dataset.
Here we used an approach for automated parameter estimation in data driven models and investigated the variability of neuron properties and underlying parameters with the resulting models.
In this work we formalize the notion of AQS reliability by determining sensitivity of AQS outputs to underlying parameters, and formulate conditions for robust simulation.
Latent variable modeling, that is statistical modeling that includes unobserved random variables that can alternatively be thought of as underlying parameters, has been used in medical research for the analysis of diagnostic accuracy and disease progression parameters in the absence of an acceptable gold standard (11, 12), as in the case of trachoma.
We therefore recalibrated the models without changing the underlying parameters.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com