Sentence examples for underlying molecular features from inspiring English sources

Survival of ovarian cancer patients is largely dictated by their response to chemotherapy, which depends on underlying molecular features of the malignancy.

This method appears very simple, but cumulative evidence found that underlying molecular features are different in right- and left-sided colon cancers.

The underlying molecular features of these deletions are thought to play a role in the deletion process, and may also be related to the severity of the disorder.

One of challenging issues in recent pharmaceutical science is to identify the underlying molecular features which govern drug-target interactions.

It is believed that the underlying molecular features of the tumors play an essential role in determining the aggressiveness of the tumors.

Asthma, eczema, and allergies represent several specific endotypes, each associated with divergent underlying molecular mechanisms, distinct clinical features, and individual treatment responses.

Despite important insights into clinical, biochemical and molecular features of these disorders, the underlying molecular pathogenesis remains poorly understood and no clearly effective therapies exist.

Epidermal barrier function is dependent upon changes to keratinocyte biochemistry and morphology that occur during differentiation [ 1, 2] and discrete tissue layers (Fig.  1b) are defined by histological features that reflect underlying molecular changes [ 1, 3– 7].

Previous studies on a well-established mouse DES model demonstrated that it recapitulates many features of the human syndrome, yet the underlying molecular mechanism is far from clear.

This can be as a result of the current characteristics of the human-disease classification which is based on clinical features and do not take into account the underlying molecular basis shared by a group of diseases.

However, the underlying molecular mechanism is poorly understood.