Sentence examples for underlying mode of action from inspiring English sources
Since synergism exists among phytochemicals, the structure activity relationship in alkaloids administered alone, or in combination with other natural or synthetic drugs or as ingredient(s) in polyherbal formulations, may elucidate the underlying mode of action of plant alkaloids.
Successfully classifying similar compounds establishes that observed transcriptional responses reflect an underlying mode of action.
To date, little is known about the underlying mode of action of the effectiveness of physical activity in treating depression.
In contrast, the underlying mode of action or the impact of SCh to elicit an MH remained unclear so far.
However, the underlying mode of action of SCh to cause an MH episode still remains unclear and needs to be evaluated in further investigations.
While both approaches discussed above have merit, depending on the underlying mode of action, there is considerable convergence in the derived TDI and NCRI estimates.
This representation may allow for the most interesting observations to be made: compounds that are predicted to modulate similar protein targets, and thus potentially share similar modes of action, are clustered together; if similar interactions are observed consistently between clusters, the underlying modes of action of each cluster might be hypothesized to interact as the cause of the synergy.
However, these biomarkers tend to be nonspecific, raise questions about their sensitivity, and do not generate insights in underlying modes of action.
Molecular cancer epidemiology is used to identify human environmental cancer risks by applying a range of effect biomarkers, which tend to be nonspecific and do not generate insights into underlying modes of action.
These clusters are the results of common underlying mode-of-action and 4 out of the 82 clusters were identified with specific molecular targets using a novel target prediction algorithm.
Phase II trial data has been extremely encouraging with regards both clinical outcome and the investigation of the underlying immunological mode-of-action.
