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Thus, this deficient glucose level compounded with the inability of brain cells to handle the available glucose (as demonstrated here) may likely be a possible underlying mechanism for neuronal degeneration in METH abuse.
12 16 An ITS design was applied for estimating the differences in prevalence of methamphetamine use before and after the Meth Project intervention, adjusting for any underlying temporal trend.
Similar LPA1-mediated chronic abnormal pain and underlying mechanisms are observed in mouse models with Meth-A sarcoma surrounding sciatic nerve (cancer model) or with chemotherapy (paclitaxel).
The underlying lesson?
Change the underlying context.
Underlying color.
Treat underlying conditions.
Look for underlying factors.
Intriguingly, circabidian (48 hr) or free-running rhythms in locomotor activity reminiscent of the behavioral patterns we detected in Slc6a3 −/− or Meth-treated mice have been observed in schizophrenic subjects (Wirz-Justice et al., 2001; Wulff et al., 2012), suggesting that DUO dysregulation underlies the rest-activity aberrations associated with schizophrenia.
Meth addicts?
Or crystal meth.
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