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Indeed the amphioxus thyroid system has recently been shown to induce metamorphosis [ 35], suggesting that mechanisms underlying metamorphosis are conserved between protochordates and vertebrates.
Investigation of miRNA expression in these tissues under conditions of programmed cell death or apoptosis may aid in establishing the critical molecular mechanisms underlying metamorphosis.
Because "Vessel" was born from many surreal dreams I was having while writing the record, the white-banded sphinx moth was used to symbolize the otherworldliness of dreams, secret knowledge and an underlying metamorphosis that this particular moth goes through in underground desert chambers.
Predictions about the metamorphoses could have been possible only within the same fixed intervals and they would simply reflect the proportion of metamorphoses seen in the data within the same interval, whereas the parametric survival regression provides a continuous time model for the underlying metamorphosis process (Fig. 2) and allows one to derive predictions for any freely chosen interval.
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The molecular mechanisms underlying the metamorphosis from an OsLRR-PSR-like ancestor gene into the first bipartite IRI-like gene have been addressed by Trembley et al. [ 10].
As mentioned previously, the molecular mechanisms underlying flatfish metamorphosis are still under debate, and eye migration and external asymmetry are apparently a separate process from somatic growth and organogenesis [ 65].
These opposite but coordinate expression changes during the non-feeding stages of females and males should pave the way for further analysis of the mechanisms underlying the metamorphosis of insects.
We next explored potential mechanisms underlying the delayed onset of metamorphosis in feeding black mutant larvae given a rapamycin diet relative to the starved larvae.
To investigate the evolution of developmental changes in gene expression underlying radial body plan development and metamorphosis, we assembled a reference transcriptome de novo and used RNA-seq to measure gene expression profiles across larval, metamorphic, and postmetamorphic life cycle phases in the sea urchin Heliocidaris erythrogramma.
Here, an analysis of gene expression profiles underlying the developmental transitions that occur during metamorphosis in both wild type and germline-deficient males and females is presented.
Two nonmutually exclusive roles of unliganded TRα in the absence of TH during premetamorphosis have been proposed: 1) repress TH target genes required to initiate metamorphosis and 2) regulate tissue sensitivity/responsivity to TH underlying the timing of developmental events.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com