The structural hallmarks of this isomerization in our simulations are similar to those identified experimentally to underlie functionally relevant transitions in the LeuT-like NSS proteins.
This study evaluates a simple molecular polymorphism (variation at the bone-growth gene RUNX2) that is thought to underlie functionally-important anatomical variation (relative face length).
Concerning the mechanisms underlying functional monogyny, L. acervorum from central Spain thus is similar to other functionally monogynous ants.
Though the underlying mechanisms functionally linking ORMDL3 to asthma remain largely unknown, a growing body of evidence supports ORMDL3 as contributing to the etiology of asthma, where it likely participates in multiple pathways important to its underlying pathogenesis.
It is hard to tease apart the extent to which these changes result from the slow physiological maturation of the auditory cortex (Moore, 2002), or changes in cognitive processes functionally underlying the activity or, more likely, a complex interaction between the two.
Collectively, these data suggest that gut microbial metabolism, PPAR-α activation, and insulin sensitivity may be involved in mechanisms that underlie physical function in functionally-limited older adults.
This result supports the hypothesis that the functional prediction of CVs could distinguish between missense mutations underlying Mendelian diseases and functionally neutral nsSNPs [15].
Molecular variation based on functionally defined genes underlying specific biochemical or physiological functions will provide the next generation of molecular markers for pearl millet.
