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Although comparative genomic studies are powerful in detecting purifying selection from sequence conservation in particular regions or at particular sites, they cannot reveal the underlying functional role of these sequences.
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In elemental interrogatives, the various interrogative pro-forms are also central, and may be analyzed as Negotiators or according to the underlying functional roles of the elements which are being queried.
Our data are in broad agreement with previous analyses showing that differences in interspecific eggshell appearance is a relatively labile trait [6] and may not serve to aid the systematic ordering of birds because of strong underlying functional causes and adaptive roles of shell pigmentation and coloration [55].
Exploration of the underlying functional annotations of trait-associated loci has thrown some light on their potential roles in pathogenesis.
The underlying functional linkage network is shown in Figure 4.
Future studies may reveal the molecular mechanisms underlying the functional role of DAYSLEEPER and its orthologs in plant development.
This recent progress underlies the functional role of miRNA in cellular transformation of liver cancer, which has largely extended our knowledge how HSCs are controlled by miRNA network, and in the development of novel miRNA-based anticancer therapies specifically targeting HSCs in the coming future.
However, the mechanism(s) underlying, such as the functional role of mitochondria, is not clear.
Despite the diagnostic and potential prognostic value of microcalcification, the mechanisms underlying the formation and functional role of microcalcification in breast cancer progression remain unclear.
What is crucial to what it is like is functional role, not underlying hardware.
However, the functional role and underlying mechanism of miR-106a involved in glioma still remain unknown and demand further investigations.
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