Sentence examples for underlying fragile from inspiring English sources

2004 A team, led by neuroscientist Mark Bear, illuminates the molecular mechanisms underlying Fragile X Syndrome and shows that it might be possible to develop drugs that treat the symptoms of this leading known inherited cause of mental retardation, whose effects range from mild learning disabilities to severe autism.

Since the discovery of the fragile X mental retardation 1 (FMR1) gene in 1991, our knowledge of the molecular mechanisms underlying fragile X syndrome (FXS) has increased tremendously [ 1].

This is important if we are to use the mouse model to adequately model the human condition, given that with increasing study, the genetics underlying Fragile X-Associated Disorders are revealed as more complicated than originally assumed.

Over the past few years, studies evaluating the effects of the polymorphic CGG trinucleotide repeat on the FMR1 gene underlying Fragile X-Associated Disorders have reported preliminary evidence for a behavioral endophenotype in human Fragile X Premutation carrier populations as well as the CGG knock-in (KI) mouse model.

Furthermore, the aging study is conducted with the kinetically fragile frozen-in structure and the underlying fragile-to-strong transition is accessed by the ultra-viscous liquid state during annealing on a long-time scale and corresponds to the last observed enthalpy equilibration decay.

Our findings strongly support the notion that genetic mechanisms other than CGG repeat expansions and deletions in the FMR1 locus can underlie fragile X syndrome.

Like frames in some gloomy, visionary science-fiction movie, they suggest the revelation of some godless, infinitely extensive existential matrix underlying our fragile human world.

Paul Grogan, an urban expert and a vice president at Harvard, explored the forces underlying this fragile revival in a book he wrote with Tony Proscio, "Comeback Cities".

The notion that any oil that may underlie the fragile refuge would affect the nation's current or long-term energy needs is ludicrous.

"You've got a market shock interacting with a very fragile underlying economic situation," he said.

Since then, the country has developed despite the fragile, underlying social balance among Malays, who are known as Bumiputra and have benefited from preferential economic treatment, ethnic Indians and Chinese.