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In about 90% of individuals with sustained hyperuricemia, impaired renal uric acid excretion is the dominant mechanism underlying expansion of the urate pool [ 1- 3].
*And get rid of this sentence: "Now, a century later we scientist can feel smug for having discovered the underlying expansion of the universe, the cosmic microwave background, dark matter, and dark energy".
The basis of the underlying expansion mutation responsible for these disorders is unknown, and problems with DNA replication, recombination and repair have all been suggested as possible mechanisms [ 6].
This is an interesting Hypothesis paper that interprets the pervasive horizontal gene transfer (HGT) in prokaryotes as a "simple but necessary consequence" of their apparent genome size constraints and the "underlying expansion dynamics of their genome through gene duplication-divergence evolution".
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This result, in turn, suggests expansion of LTR retrotransposons as a likely molecular mechanism underlying genomic expansion at the base of the salamander clade.
The current availability of several genome sequences allows the study of the evolutionary steps underlying the expansion of a gene family by detailed characterisation of lineage-specific expansions.
There are multiple components underlying CAG expansion mediate disorders, which involve aggregate-prone polyQ proteins as well as untranslated CAG repeat expansions at the mRNA level.
Meanwhile Berenberg said: Capita's 2015 results were largely in line with expectations, driven by 4% organic growth and a 20 basis point underlying margin expansion (up 40 basis points including disposals).
That implies, in turn, that underlying economic expansion in the first quarter was also around 0.8%.In this section And now for the good news So far, so good Learning without frontiers Aisle change The ties that bound Street smarts ReprintsThis means that the economy has in effect been growing at an annualised rate of 3.2% since the start of 2010.
For the exploration of the driving mechanisms underlying urban expansion, 20 explanatory variables are then categorized into three groups: characteristics, density, and proximity.
The molecular mechanisms underlying their expansion in obesity and following body weight reduction are poorly defined.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com