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Objective The mechanism underlying exercise intolerance in chronic heart failure is still unclear.
Therefore assessment of measures beyond 6MWD and peak VO2 measurements is needed to identify the specific pathophysiology underlying exercise intolerance.
The putative sex-specific QTL further suggest that the genetic architecture underlying exercise capacity is different in males and females.
If clinical symptomatology of CHF resembles that of ID, one can simply imply impaired iron homeostasis as one of the mechanisms underlying exercise intolerance in CHF.
Furthermore, the sex-dependent differences in exercise capacity and the putative sex-specific QTL imply that the genetic architecture underlying exercise capacity might be different between males and females.
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The mechanisms underlying exercise-induced angiogenesis and vasculogenesis in skeletal muscle are well defined [ 43, 44].
Given that the underlying exercise-induced transcriptional mechanisms regulating muscle mass in vertebrates are not fully understood, here we investigated the cellular and molecular adaptive mechanisms taking place in fast skeletal muscle of adult zebrafish in response to swimming.
These data suggest that alteration of transient outward current plays an important role in exercise-induced electrical remodelling and that the rat model of voluntary exercise mimic some human responses and is therefore useful for the study of the cellular mechanisms underlying exercise-induced electrical remodelling.
Numerous mechanisms may underlie exercise limitation in CHF, and among them inadequate oxygen supply and impaired oxygen utilization by the exercising skeletal muscle.
In order to determine the neuroprotective mechanisms underlying treadmill exercise, expression of Hsp 70 and Hsp 27 mRNA was examined in control, treadmill exercise, and volunteer exercise groups (Fig. 4a, b).
Underlying the exercise is a rich political discussion mostly about what the Republicans hope to achieve.
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