Exact(2)
On the other hand, Bressloff [18, 19] showed how the path-integral representation of the master equation can be used to investigate large deviations or rare event statistics underlying escape from the basin of attraction of a metastable state, following along analogous lines to previous work on large deviations in chemical master equations [24 26].
The majority of patients on early trials of these drugs develop secondary resistance and subsequent disease progression and it is, therefore, critical to understand the underlying escape mechanisms leading to resistance.
Similar(58)
While approximately 20% of HCV-infected individuals spontaneously clear infection, the mechanism of spontaneous clearance remains poorly defined and a greater understanding of both the viral clearance process and of viral strategies underlying immune escape is necessary for future vaccine development and more effective management of infection.
Moreover, the finding that c-Myc levels are elevated in early passage MEFs lacking p53 (Fig. 3D), raises the possibility that c-Myc upregulation in this setting constitutes a critical and perhaps general mechanism underlying senescence escape and oncogenic progression associated with loss of p53.
Photons flowing from below, trapped by the underlying layers, finally escape.
Not surprisingly, camp and travel -- with their underlying themes of escape -- are common denominators that frame summer associations.
The mechanisms underlying tumor immune escape are still to be fully dissected.
To determine the genetic architecture underlying diversity in escape behavior in global populations of C. elegans, we conducted genome-wide association mapping of the 66 behavioral metrics that describe the escape response to a thermal stimulus of 0.4° (File S5, tab wild-isolate phenotypes).
However, the mechanisms underlying tumour cells escaping from NK cell lysis are still not understood.
Therefore, neat PVC and TNTs-PVC allow the heat to easily transfer from combustion surface to polymeric matrix and flammable organic volatiles to escape from underlying matrix to combustion zone.
Since the lipid layer serves as a barrier for the underlying aqueous tear to escape, it may reduce tear evaporation [ 23– 25].
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