Sentence examples for underlying disruption from inspiring English sources

There is a long-standing debate in the field of endocrine disruption as to whether it is more important to reveal potential disrupting effects or to address the mechanisms of action underlying disruption.

However; CH patients demonstrate poor sleep quality both in- and outside of active cluster bouts [10] highlighting a potential underlying disruption of sleep homeostatic regulatory mechanisms separate from the influence of the nocturnal attacks.

We investigated the molecular mechanisms underlying disruption of intestinal symbiosis in patients carrying Nod2 mutations.

Human imaging studies reveal an underlying disruption in the reward systems in addictive behaviors including alcohol use disorder and binge eating [1], [2], [3] and common neurobiological mechanisms may underlie these diseases.

Given that human imaging studies also reveal an underlying disruption in the reward systems in addictive behaviors, including alcohol use disorder and binge eating [1], [2], [3], we suggest that underlying neurobiological mechanisms for such addictive behaviors include central ghrelin signalling at the level of the reward systems, such as the cholinergic-dopaminergic reward link [43].

The loss of an MT-binding protein represents a mechanism underlying disruption of disc structure and/or function.

Although recent evidence suggests that genetically engineered GPRC6A receptor knockout (KO) mice are susceptible to develop subtle endocrine and metabolic disturbances, the underlying disruptions in energy metabolism are largely unexplored.

Since then, numerous mechanisms underlying the disruption of phagosome maturation have been identified in M.tb infection (Russell 2011; Russell et al. 2013).

Thus, a holistic and comprehensive understanding of the mechanisms underlying thyroid disruption, may lead to changes in public policy and awareness, and make it possible to limit adverse outcomes for future generations.

Suppression of further LINE-1 activity will not correct the underlying gene disruption causing the disease.

Currently, the mechanism underlying the disruption of MDM2-mediated mutp53 degradation in tumors is poorly understood.