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Due to the curse of dimensionality, the underlying dependence relationships between these random variables are difficult to capture.
Adaptations in the NF-κB system may be essential for persistent neuroplastic changes and neurodegeneration underlying dependence to alcohol and associated impairment of cognitive functions.
The results found by multivariate analysis do not agree with those of the bivariate analysis, further exemplifying the underlying dependence on age.
The vast majority of research regarding the effects of abused drugs and the neural changes underlying dependence has been focused on neurotransmission within and between the frontal cortex (Fcx), nucleus accumbens (NAc), dorsal striatum (DS), central nucleus of the amygdala (CeA) and bed nucleus of the stria terminalis (BST).
The latter is a good exposition of the model as it pertains to various types of short-term plasticity seen in the central nervous system, and the underlying dependence of the plasticity is based on physiologically relevant dynamics of calcium influx and decay within the presynaptic terminal.
This adjacency graph approximates the underlying dependence structure of the sample population and the eigenvectors of the associated graph Laplacian contain useful geometric structure information (for details see the references above).
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Although it remains unclear how pDBIs and bDBIs are produced after morphine intake in humans, our study provides a new mechanism of morphine tolerance and dependence underlying addiction in animals which may help future efforts treating addicted patients.
In addition, her work has focused on understanding the neurobiological mechanisms underlying alcohol dependence and what goes into the risk to develop alcoholism. 1. Finding effective pharmacotherapies for individuals with alcohol dependence and comorbid psychiatric disorders.
Human twin studies have suggested that there is a substantial genetic component underlying nicotine dependence, ongoing smoking and ability to quit.
The possible mechanisms underlying the dependence of the transformation temperature on these features is discussed based on a Landau-type phenomenological model.
Persistent up-regulation of NR2B gene expression by chronic intermittent alcohol treatment may serve as one mechanism underlying ethanol dependence behaviors.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com