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"And with his underlying dementia I'm not sure how much of a recovery we can expect".
The chapter discusses the resting glucose metabolism in typical and atypical PD, mechanisms underlying fluctuations and dyskinesias, mechanisms underlying dementia in PD, and MRI volumetry.
"And with his underlying dementia I'm not sure how much of a recovery we can expect". He added that my father's sodium had fallen to 128 critically low, yet another sign of severe damage to the brain tissue.
Psychosis usually develops late in PD, often due to underlying dementia and as a result of anti-PD medication.
Finally, we assume that the combination of peripheral and CSF markers may be utilized to categorize patients since early stages of dementia and to understand mechanisms underlying dementia.
It is conceivable that underlying dementia resulted either in poor symptom recognition by the affected patients or may have impaired their ability to report symptoms.
Similar(31)
Further autopsy studies on patients with TTR meningovascular amyloidosis are necessary to elucidate the significance of tauopathy in the cognitive impairment and to further delineate the neuropathologic changes that underlie dementia.
This is in keeping with the category-general deficits observed in the context of the ATL-focused atrophy underlying semantic dementia [ 17].
Accordingly, increases in the toxic forms of Aβ lead to a cascade of events - including inflammation, synaptic loss, ionic imbalance, and abnormal phosphorylation of proteins (including tau) - culminating in cell death and underlying clinical dementia.
The study did not entirely rule out the possibility that a proportion of patients enrolled into this study had Alzheimer's dementia rather than vascular dementia, and that the beneficial effect of the drug was due to its activity associated with the Alzheimer's disease pathology (Malouf and Birks 2004) rather than with the pathological changes underlying vascular dementia.
However, diverse molecular and cellular pathologies can give rise to common patterns of dysfunction at the neural systems level, and therefore recent studies have begun to characterize the mechanisms underlying Parkinsonian dementia from this perspective, which provides a more generalizable model.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com