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SARS is difficult to recognize in hospitalized patients with a variety of underlying conditions in the absence of epidemiologic links.
However, demographic variables and distribution of underlying conditions in the real life setting are expected to vary from those of strictly selected patients in randomized studies (e.g., exclusion of subjects with reduced life expectancy, severe organ impairment and/or receiving concomitant medications), and might explain the differences in terms of response observed in our study.
"The underlying conditions in the airline market have improved and have made the original bid look a bit skinny," said Matthew Crowe, the transportation analyst at JPMorgan in Sydney.
We considered a modified risk-based strategy, where only individuals aged less than 65 with underlying medical conditions were prioritized to receive vaccine (versus individuals of any age with underlying conditions in the main analysis) prior to implementing an attack rate- or outcome-based allocation strategy.
These could include the small sample size, the heterogenous characteristics of the participants, other underlying conditions in the participants, and the stimulus and instrumentation used.
Given that diseases of the musculoskeletal system are not often considered immediate causes of death, completeness of recording underlying conditions in the death certificate becomes crucial when analyzing mortality of these diseases.
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Underlying conditions in patients with and without hypoxic hepatitis at the time RRT was initiated.
According to Louie and colleagues [ 5], diabetes and obesity were the most frequently identified underlying conditions in fatal pandemic 2009 influenza A (H1N1) infection cases older than age 20 years world wide.
This electronic clinical record system will be used to classify vaccination status as well as to identify comorbidities or underlying conditions in cohort members and establish baseline characteristics of the cohort at study start.
This suggests that a greater proportion of healthcare dollars was spent to treat underlying conditions in higher risk patients than in low-risk patients.
Our study was focused on relative comparisons of disease severity over time, geography, and treatment groups, and we assumed similar underlying conditions in comparison groups.
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