Recognize the general principles underlying common statistical procedures.
The finding is part of a continuing wave of discoveries about the genes underlying common diseases.
The mechanism of AD dysfunction might underlie the common features, while the regional feature would be the biomarker for the specific diseased tissues.
Thus, it is plausible that deregulation of Pol I transcription is the underlying cause of these common features [ 20].
Mitochondrial proliferation and functional impairment are common features underlying cardiac disease in Barth syndrome, Friedreich's ataxia, and mtDNA mutation disease.
These basic characteristics have led to the development of a system-level approach that is not only intended to generate a human cancer map of the expression of candidate antigens, but also to highlight common features underlying tumours of unrelated histological origin, thus improving our basic knowledge of tumour complexity [ 21].
SBMA belongs to a family of nine polyglutamine repeat expansion diseases including Huntington's disease, dentatorubral pallidoluysian atrophy and six spinocerebellar ataxias, which share many common features and underlying pathological mechanisms (Ross, 2002; Gatchel and Zoghbi, 2005).
It might be expected that common features should underlie the different pathways that lead to or protect from the phenotypes in diverse neurodegenerative diseases.
Therefore, an understanding the regulation of chloroplast division, in which PG splitting is involved, will shed light on the common features which underlie the establishment and further evolution of permanent endosymbiotic relationships.
Overall, our network analysis, supported by the example of TAF1, suggests that common features underlie the genetic interaction spectrum of mutants with genome instability.
We developed a method to sequentially identify clusters of correlated genes that control the prognostic power of these gene lists with the goal of identifying the common underlying biological features of these classifiers.
