Sentence examples for underlying challenge is from inspiring English sources

The underlying challenge is to convince people that the threats are real and life-changing, and that there is something that can be done to change our predicament.

"The underlying challenge is — 'Do you trust the insurance companies?' " said Mike Davis, a health technology analyst with the HIMSS Analytics consulting firm.

The underlying challenge is the lack of state-of-the-art models applicable to broad spectrum of microbial organisms for accurate description of treatment history.

Thus, an important underlying challenge is the production of high-performance and robust protein capture agents at low cost.

The underlying challenge is to identify early enough those with PALF for whom chances of survival without a transplant are null, so that these can be super-urgently listed.

Writers work for long hours and they are happy because they make a lot of money, however, there are underlying challenges that are associated with the nature of this work.

Although a broad spectrum of natural products synthesized by cyanobacteria has potential bioindustrial applications, the underlying challenge in commercialization is to achieve production yields that meet realistic scalable production.

"That is the underlying challenge upon which we and our partners such as the Government of Japan have to maintain a clear focus".

Egypt, the most populous Arab state, served as a model: the army officers who grabbed control in a 1952 coup established an autocratic regime, in effect a dynasty of fellow soldiers, that survived until 2011.Though recent Arab revolts have made rulers such as Egypt's Hosni Mubarak the focus of popular rage, the underlying challenge of the Arab spring has been to the "dynasties" they represented.

A key factor underlying the clinical and therapeutic challenge is multiple layer of heterogeneity that exists in myeloma.

The underlying computational challenges are addressed by means of core FSI methods (i.e., the ALE VMS formulation, weakly enforced no-slip boundary conditions, the sliding-interface technique, and a quasi-direct coupling strategy), as well as special FSI techniques developed for this problem class.