Sentence examples for underlining the requirement for from inspiring English sources

Further in silico analysis revealed that 18 out of 19 reference probes hybridize to regions subject to variation, underlining the requirement for designing new reference probes against variation-free regions.

The specific chemistry and quality of the reaction components play an important role in optimizing Q-PCR reactions, underlining the requirement for critical evaluation in order to overcome subjectivity inherent to the Q-PCR assay [ 6].

It is important to note that many alternative splicing events display precise tissue and developmental regulation, underlining the requirement for the correct biological context when examining functional and therapeutic insights into alternative splicing (Takeuchi et al., 2010; Calarco et al., 2011).

The recent report of a Spanish genotype, genetically divergent from the strains circulating in Italy, which is not detected by PCR systems previously reported in Italy, underlines the requirement for a large program of strain isolation and full-length genome sequencing to achieve this goal.

Collectively our analysis of the transcriptional response to PH reveals that lack of UPF2 leads to a block in liver regeneration at a stage before dedifferentiation and entry into the cell cycle and further underlines the strong requirement for UPF2 in proliferating cells.

The data from the present work underline the requirement of adequate levels of HIF-1 for the viability of chondrocytes and for the maintenance of the integrity of hypoxic articular cartilage.

It has been previously shown that there is a correlation between size of disease and the requirement for further surgery, underlining the need for accurate preoperative assessment (Vicini et al, 2001).

Trainee radiologists should be aware of the potential for such alterations in practice and the requirement to be flexible throughout their career, underlining the need for good basic training in all modalities and continuing medical education.

Section 3 describes the objectives and requirements of the system's design, underlining the need for a distributed architecture and the use of local communications.

Substance abuse will often reduce a person's capacity to self-care; underlining the need for a unique approach to diabetes management in this group in terms of skill-mix and service requirements.

The requirement for ATP in such reconstitution studies underlines the key role of the general class of ATP-dependent chromatin remodelers in establishing nucleosome positions in vivo (Clapier and Cairns 2009).