The EAACI underlines the requirement of such studies in a task force report on dose response relationship in allergen-specific IT.
Our finding that 50% of the NNT-reporting articles with survival time data used inadequate calculation methods underlines the requirement to point out that special methods based on survival time techniques have to be used to calculate NNTs in this situation.
The recent report of a Spanish genotype, genetically divergent from the strains circulating in Italy, which is not detected by PCR systems previously reported in Italy, underlines the requirement for a large program of strain isolation and full-length genome sequencing to achieve this goal.
But he concedes that the editors' code committee may need to frame a change to the code of practice in order to underline the requirement on journalists to inform people before they plan to write about them.
Further in silico analysis revealed that 18 out of 19 reference probes hybridize to regions subject to variation, underlining the requirement for designing new reference probes against variation-free regions.
They underline the requirement to assess biotransformation effectiveness, both in terms of substrate utilisation and product formation, in multiple strains, in order that the optimal strain might be selected.
The specific chemistry and quality of the reaction components play an important role in optimizing Q-PCR reactions, underlining the requirement for critical evaluation in order to overcome subjectivity inherent to the Q-PCR assay [ 6].
The data from the present work underline the requirement of adequate levels of HIF-1 for the viability of chondrocytes and for the maintenance of the integrity of hypoxic articular cartilage.
It is important to note that many alternative splicing events display precise tissue and developmental regulation, underlining the requirement for the correct biological context when examining functional and therapeutic insights into alternative splicing (Takeuchi et al., 2010; Calarco et al., 2011).
This requirement motivated Parmenides (fl.
