Sentence examples for underlines a role from inspiring English sources

However, our finding of an increased expression of MIP-3α mRNA in RCC cell lines, as well as in RCC tissue compared to mRNA derived from normal kidney, underlines a role for an increased expression of MIP-3α in homing or recruitment of immature DCs to RCC tissues.

These data underline a role for Smad3 in α-synuclein and DA homeostasis, and suggest that modulatory molecules of this signalling pathway should be evaluated as possible neuroprotective agents.

These results underline a role of the RANKL/OPG system in the pathophysiology of breast cancer.

This observation underlines a dual role for Lyn as a positive effector in Epo signaling and a negative effector in Kit signaling and presents Lyn as a major mediator of the balance between Epo and SCF responsiveness during proliferation of proerythroblastic cells.

An accumulating body of evidence clearly underlines a significant role of 5-hydroxytryptamine (serotonin, 5-HT) in development and progression of LV hypertrophy (LVH) and fibrosis [ 4– 6].

Perinecrotic activation of HIF-1α in invasive tumors underlines a dual role of HIF-1α by regulating both pro-survival and pro-death processes.

Furthermore, the increase of miR-184 expression in the islets of ob/ob mice after restoring insulin sensitivity further underlines a dynamic role for the miRNA pathway in regulating β cell growth and function according to the demand for insulin.

Nevertheless, the lower reactivity to the TIII1-CG fragment (the complete TSP3 and C-terminal globule fragment), compared to all the fragments containing the EGF repeats (pCOMP, mCOMP, EGF1-TIII8 and EGF1-4) underlines an important role of the EGF repeats in the immune response.

He underlines an important role of the Commission in reducing cross-border obstacles by proposing legislation or funding mechanisms or by supporting Member States in creating better arrangements and deepening their cooperation to break down the barriers in the border regions.

Moreover, some accompanying symptoms of migraine are mediated by the dopaminergic system (nausea, vomiting), underlining a possible role in clinical susceptibility to migraine.

Our results underline a crucial role for Lrp1b in development.