Sentence examples for underline a role from inspiring English sources

These data underline a role for Smad3 in α-synuclein and DA homeostasis, and suggest that modulatory molecules of this signalling pathway should be evaluated as possible neuroprotective agents.

These results underline a role of the RANKL/OPG system in the pathophysiology of breast cancer.

However, our finding of an increased expression of MIP-3α mRNA in RCC cell lines, as well as in RCC tissue compared to mRNA derived from normal kidney, underlines a role for an increased expression of MIP-3α in homing or recruitment of immature DCs to RCC tissues.

Our results underline a crucial role for Lrp1b in development.

These findings underline a crucial role of platelets in the initiation of leukocyte-endothelial interaction.

Taken together, these results underline a dual role for nuclear IL-1α depending on cellular context.

Taken together, these data underline a crucial role of FreB in adaptation to iron starvation and reveal that the siderophore system increases resistance against copper starvation.

13 These findings underline an important role of intracellular nucleic acid metabolism in the maintenance of immune tolerance by preventing an inadequate innate immune response induced by recognition of self nucleic acids.

GFAP and GDNF as signs of activated EGCs are increased in the inflamed mucosa of patients with UC and infectious colitis, which underline an unspecific role of EGC in the regulation of intestinal inflammation.

The data presented herein support the hypothesis that the lack of peripheral tolerance can lead to SLE-like features and thus underline an important role of Tregs in the pathogenesis of SLE, as suspected on the basis of previous reports on defective Treg function in active lupus [ 9].

Moreover, some accompanying symptoms of migraine are mediated by the dopaminergic system (nausea, vomiting), underlining a possible role in clinical susceptibility to migraine.