Two basic premises underlying the description to follow are that (i) astaxanthin uptake, transport and delivery are closely associated with fatty acid uptake, transport and delivery, and (ii) major features of astaxanthin absorption, metabolism and transport in salmon are similar to the absorption, metabolism and transport of xanthophylls in mammalian systems.
These observations also underlie the previous descriptions regarding the various mannose-resistant hemagglutination (MRHA) and mannose-sensitive hemagglutination (MSHA) phenotypes as well as serotypes in E. tarda strains [2], [32], [33].
For this reason, the data underlying the quantitative description is reported in detail in the appendices.
Roadblocks from clinical advances to widespread implementation, together with lag time-to-benefit may underlie the 20 years since the description of the antiproteinuric effect of RAS blockade to the observation of decreased age-adjusted incidence of endstage renal disease due to diabetic kidney disease.
Thus, biophysically detailed AP modelling predicted essential aspects of the pharmacological profile of ivabradine, based on the description of underlying ionic current mechanisms.
Understanding of the mechanisms underlying shock and the description and classification of shock states came much later and one of the key early contributors to this field was Dr Max Harry Weil, who died last year [ 5].
The development of geographical information systems (GIS) and the interoperability between these systems demands new requirements for the description of the underlying data.
It has been hoped that the description of the underlying molecular changes accompanying these morphologically defined stages, and at least a partial understanding of their significance, would enable pathologists to confirm or refute their models and to allow individual cases to be placed in the sequence.
Both facilities are possible thanks to the chosen internal representation mechanism, which is a mathematical model of the description, and to an underlying formal calculus that allows the description to be correctly manipulated.
Negations cannot be properly expressed in the description logic ℰ ℒ underlying SNOMED CT.
These results indicate that by taking into account the underlying kinetic description of the interactions, the OptCircuit framework is able to expand upon possible circuit designs by drawing from architectures that may not be valid based on digital logic viewpoint though adequately meet the imposed requirement due to the careful matching of kinetic parameters as often observed in nature.
