Sentence examples for undergone extensive changes from inspiring English sources
The role of the psychiatric emergency services has undergone extensive changes following a significant downsizing of the number of psychiatric hospital beds during the past decades.
Since the establishment in 1945 of a formal international monetary system with the IMF empowered as its guardian, the world has undergone extensive changes politically and economically.
At the same time healthcare systems in the region have undergone extensive changes [ 4], with increases in the provision of mental health services [ 2].
Thus, during evolutionary history from prokaryotic to eukaryotic stages, the size and content of selenoproteomes have likely undergone extensive changes.
The chemistry of relative permeability modifiers has also undergone extensive change; the most notable result of which has been to prolong the life of water control treatments using relative permeability modifier (RPM) polymers.
A roentgenogram taken 274 days after the injury (Fig. 12) showed union of the fractures in both astragalus and os calcis but the body of the os calcis had undergone extensive change.
The sample underwent extensive changes in hydroxyl, carbonyl and amorphous region of infrared upon irradiations.
Second, methylation of CpGs are dynamic epigenetic marks that undergo extensive changes during cellular differentiation, particularly in regulatory regions outside of core promoters.
These cells typically undergo extensive changes in protein expression and secretion, resulting in the development of a senescence-associated secretory phenotype (SASP the persistent secretion of pro-inflammatory growth factors, cytokines, chemokines, proteases and extra-cellular matrix components16.
The structure of aggrecan does not remain constant throughout life, but undergoes extensive changes due to variations in synthesis both within the chondrocytes and the ECM (Figure 5).
Human skin undergoes extensive changes in appearance (e.g. wrinkle formation) and mechanical function (loss of both compliance and resilience) with age [1 3].
