In the 'interface-sliding' pathway, the TMD enters the cytoplasm through the gap between the translocon and ribosome, prior to undergoing membrane integration; a trajectory thus exhibits this pathway if a TMD visits IS4 on the way to membrane integration.
Potential inhibitors would bind to two metal ions in the active site of HIV IN to prevent human DNA from undergoing the integration reaction.
In the 'interface-sliding' pathway, the TMD enters the cytoplasm through the gap between the translocon and ribosome, prior to undergoing membrane integration.
The new HTT passenger capsule will still undergo final "integration and optimization" at the company's research and development facility in Toulouse, France before delivery to the still-unspecified customer.
Financial capital of the 12 members will undergo deep integration under the TPP framework and will be mutually pegged.
The GR is also supposed to undergo the integration process, but in January 2007, only one battalion had been announced as been integrated.
Importantly, we have defined a specific population of cells that undergoes robust integration into the host DG after transplantation.
They must also be biosynthesized in cells or by microorganisms, risking contamination in therapeutic applications, and can undergo genomic integration, potentially causing cancer [7].
The new cells added to the OB and DG circuits undergo functional integration [16], [17], and this process is thought to be important for learning and memory [5].
As far as we know, the exclusive segregation of vomeronasal afferences occurs in all species with a two-pathway VNS, and no study has suggested that glomeruli of both pathways may undergo synaptic integration by intrinsic AOB neurons.
