The phrase "undergo major changes" is correct and usable in written English.
You can use the phrase when you want to express that something has been through significant transformation or alteration. For example, "After the new policy was implemented, the company's structure underwent major changes."
By observing spatial changes of gene expression during myogenesis, two predominant expression profiles were observed: one profile for which sub-components of the Z-disk and the majority of the costamere did not undergo major changes from myoblast to myotube; and another profile for which the majority of myofibril filament system proteins were substantially up-regulated.
The dozen years he has been gone have seen India undergo major changes.
In recent years, scientific perspective on sexual response in women have undergo major changes.
The IPCC estimates that about one-third of the world's forests would undergo major changes in vegetation types.
But under the plan the administration has developed and now advocates, the officials said, it would later undergo major changes.
Finally, the Amblève River did not undergo major changes in style during the last 2000 to 5000 years, even though floodplain sedimentation rates increased tenfold during the last 600 years.
Their clothes are designed expressly not to be noticed, in styles that used to undergo major change about once every 20 years.
His supporters were enthusiastic, and an Italian Communist said that if he succeeded in putting his precepts into action, the economy would undergo major change.
About the same time, rod materials were undergoing major changes.
Two of the four methodologies have undergone major changes.
Mayor Matthew R. Godfrey conceded that his city had been undergoing major changes in recent years.
