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Secondly, by applying CUSP, we have examined the range of variations in diverse domain superfamilies by distinguishing structurally conserved blocks (of similar nature and lengths) from indels (regions susceptible to undergo length differences).
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Transported peptides undergo length-specific trimming by ERAP1 (endoplasmic reticulum aminopeptidase associated with antigen presentation 1) and are loaded onto empty HLA class I molecules (with involvement of tapasin and the chaperone molecules calnexin, calreticulin and ERp57) [ 11– 11].
The same domain has also undergone length variation and segmental duplications in different primate lineages [ 25].
The telomere length dynamics of telomerase-negative immortalized cells suggested that this mechanism is based on recombination: single telomeres undergo dramatic length fluctuations during cycles of cell division, with rapid shortening and rapid lengthening events (3, 4).
This mechanism of muscle length adaptations, termed 'myogenic', has not been demonstrated in human muscles, but it has been intimated by therapeutic lengthening studies showing that both healthy and neurologically impaired human muscles can undergo increased length adaptations in the presence of muscle activations.
Do they undergo dynamic length changes under stress?
These sequences undergo considerable length variations due to DNA polymerase slippage and as a consequence are highly mutagenic [ 58].
To select which cDNA clones from 567 contigs and 1,091 singlets to undergo full-length sequencing we used homology analysis.
To compare the accuracy of the Actim Partus test and fetal fibronectin (fFN) test in the prediction of spontaneous preterm delivery within seven days in symptomatic women undergoing cervical length measurement.
The reversible shape change is accomplished by a core design which forces an inactive face sheet to martensitically deform in tension when the opposing face sheet undergoes a length change.
Equal rotations of the three rows of stereocilia then imply that the tip-link/gate/membrane complex would undergo a fractional length change.
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