Sentence examples for undergo down from inspiring English sources

Furthermore, these results demonstrated that miR-301a and miR-454 are indeed co-regulated in SCD and undergo down regulation by an as yet unidentified process.

If the sampling frequency of the second time-frequency analysis does not undergo down-sampling, the final time-frequency diagram will exhibit serious distortion.

CKR in term of its ability undergo down-regulation, activation, recruitment of signaling proteins and to stimulate cellular responses is identical to VEGFR-2 [14] [20], [21], [21] and data presented in this manuscript.

The composition of aqueous humor proteins changes dramatically [13], and antioxidant proteins undergo down-regulation, in glaucoma; this leads to increased concentrations of nitric oxide synthase 2 and other proteins that, in physiological conditions, are segregated inside the functional mitochondria of TM cells [14].

Of the remaining gliotoxin biosynthetic genes, while not significant, with the exception of A. fumigatus gliZ and gliI which did not exhibit altered expression, and gliJ which appeared to undergo down-regulated expression, increased expression of the remaining genes was observed in A. fumigatus ∆ gliT upon exposure to exogenous gliotoxin.

Although, the overall expression of TrkA in MM biopsies correlates with worst prognosis, phosphorylated TrkA is detected in a considerably smaller fraction of metastatic MMs compared to the primary samples [ 32], suggesting that activation of TrkA signaling might be important for the early onset of the tumor and might undergo down-regulation once the tumor becomes metastatic.

However, the angiogenesis inhibitor pent(r)axin-related gene (PTX3) is also up-regulated, while other genes critical for the angiogenic process, such as plexin B1 (PLXNB1, semaphorin receptor), tissue kallikreins KLK9, KLK11, and KLK12) [ 12], and DSG2 (a cadherin that mediates homophilic cell adhesion), undergo down-regulation in SSc-MVECs.

The differences that we observed in the fetal brain may point to a more complex effect of XO monosomy, where some genes underwent down regulation upon X chromosome loss while others were upregulated.

In contrast, genes that exhibited QLVD and QLCU expression profiles underwent down and up regulation respectively but reached steady state expression levels before the experiment was terminated.

Cluster B, which might correspond to somatic genes undergoing down regulation as the testis matures, was found to contain many genes involved in various developmental processes.

Finally, the observation that the presynaptic marker bassoon undergoes down-regulation in AE3−/− (Fig. 3i, 3j) indicates further pathological changes.