Sentence examples for undergo disorder from inspiring English sources

p53-NTD interacts with multitude of protein factors that include molecular chaperones such as HSP90 [24], CHIP [25], HSP70 [37], and MDM2 [38] and it was shown to undergo disorder to order transition by interacting with MDM2 [39].

In conclusion, miscible POEGMA-P2VP diblocks undergo disorder to order transitions when cast from acid-containing solutions due to protonation of the P2VP block.

MoRFs are short order-prone motifs flanked by disordered regions that are involved in molecular recognition and are able to undergo disorder-to-order transition during binding to a specific partner.

One of the most intriguing features of IDPs is their ability to undergo disorder-to-order transitions upon binding in order to perform their function.

Indeed, many IDPs undergo disorder-to-order transitions upon binding to proteins, nucleic acids, or lipids.

Upon binding to kinetically entrapped RNA molecules, many of these chaperones undergo disorder-to-order transitions.

Many IDPs and IDRs undergo disorder-to-order transitions upon binding, which is crucial for recognition, regulation, and signaling [ 1, 4, 14, 28, 34- 37, 131- 133].

Finally, the tendency of MoRFs and preformed elements to undergo disorder-to-order transitions and the statistics used for their detection means that these features tend to be slightly longer than annotated linear motifs.

Summary: ANCHOR is a web-based implementation of an original method that takes a single amino acid sequence as an input and predicts protein binding regions that are disordered in isolation but can undergo disorder-to-order transition upon binding.

Among the various functions found for disordered regions, even superficial analysis of "natively unfolded" proteins revealed that many of them undergo disorder-to-order transitions when stabilized by binding with specific targets [ 37].

Importantly, MoRFs undergo disorder-to-order transitions upon binding their interaction partners (i.e., folding upon binding), and often the unbound form of these preformed elements is biased toward the conformation that they adopt in the complex.