Sentence examples for undergo class from inspiring English sources

To produce a functionally diverse antibody repertoire B lymphocytes undergo class switch recombination.

Within the germinal center (GC), antigen activated B cells undergo class switch recombination (CSR) and somatic hypermutation (SHM).

The GC is the site where antigen activated naïve B cells migrate, proliferate and undergo class switch recombination, antibody gene diversification and affinity maturation [10].

The results demonstrated that human B cells developed by DRAG were functional as they secreted all human immunoglobulin classes, whereas those from control mice were impaired in their ability to undergo class switching and secreted only IgM.

It is known that in mice, Th1 biased T helper cell responses favor the production of antigen specific IgG2a and IgG3 while Th2 responses prompt B cells to undergo class switch recombination towards IgG1 and IgE [24], [25], [27].

B1 B cells have also been found to undergo class switch recombination from IgM to IgA.

She said the parents were ordered to undergo classes in child care.

China is still undergoing class struggle, Mr. FlorCruz recalls being told by his minders.

Since the CD27−IgD− cell subset, which appears to be enhanced in the peripheral blood of patients with SLE [36], [37] might include B cells which may have undergone class switching simply by exposure to TLR-ligands or cytokines such as IL-10 or IL-21 or BAFF [38], [39], [40], [41], this subset was considered to be heterogeneous.

Thus the class-switched transcripts are derived from IgM+ cells that apparently have already undergone class switching but have yet to turn off IgM surface protein expression.

Their progenitors, the CD19+ plasmablasts, have undergone class switch on their differentiation pathway to further develop to antibody-producing CD19- plasma cells.