N- and R-type channels do not undergo activity-dependent recruitment and remain loosely coupled to the secretion.
Inhibition of the sensory neurons has now also been shown to undergo activity-dependent enhancement when action potential activity in the sensory neurons is paired with inhibitory transmitter.
By analogy with 'silent synapses' (i.e. synapses that contain only NMDA receptors), Type 2 cells are candidate 'silent cells' that may undergo activity-dependent acquisition of functional fast-conducting AMPA receptors with maturation.
Second, the synaptic responses may be saturated and simply could not undergo activity-dependent potentiation.
CapZ localization in the hippocampal dendritic spines has been recently shown to undergo activity-dependent, synapse-specific regulation in a rat model of dementia[11].
Using techniques that allowed direct access to presynaptic mechanisms, we consistently found that small amounts of APP are present in synaptic vesicles, which undergo activity dependent secretion.
Dendritic spines undergo bidirectional morphological changes in response to neuronal activity, and the morphology of individual spines is correlated with synaptic strength and their capacity to undergo activity-dependent plasticity [4] [6].
