In contrast to mitosis, germ cells undergoing meiosis actively generate genetic diversity through induction of programmed DSBs, which are repaired through HR.
Cells in the pericycle actively undergo cell division and proliferation (Dubrovsky et al. 2000).
Mitochondria actively undergo fusion and fission, which determine mitochondrial morphology (Twig et al., 2008; Wang et al., 2012).
Abundant VASA positive cells were found in sections of seminiferous tubules in Hdac6 overexpression testis, in contrast to some testis of WT mice (Fig. 1E), indicating that testis of old Hdac6 overexpression males still actively undergo spermatogenesis and meiosis.
Thus, some ESCM proliferate in early cultures, but with continued cultivation time, cells stop dividing and actively undergo a maturation process characterized by binucleation concomitant with changes in gene expression (e.g., calsequestrin, ssTnI, cTnI and ANF).
Therefore, NPCD cells remain static, whereas both the EPCD and LPCD actively undergo PCD.
By contrast, under matrix detached conditions, the parental HME16C cells are non-proliferative, but do not actively undergo anoikis.
We also concluded that PD-MSCs do not actively undergo differentiation into chondrocytes since very few portions of PD-MSCs survived after coculture.
These studies together demonstrated a new mechanism of cellular interaction between MSCs and chondrocytes: MSCs support chondrocyte proliferation and cartilage matrix deposition rather than actively undergo chondrogenic differentiation.
These findings suggest that the quality of HIV testing service should be enhanced to ensure that persons with a high risk of HIV infection undergo the tests more actively to prevent the spread of HIV infection.
