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Since 1 January 2011 all new patent-protected pharmaceuticals undergo a systematic assessment of the additional benefit upon market entry in Germany.
"You need to undergo a systematic desensitization".
Consequently, it has been suggested that patients with unilateral germ-cell tumours should undergo a systematic contralateral testicular biopsy at the time of orchidectomy to evaluate intratubular germ-cell neoplasia and identify patients who may develop a second germ-cell tumour (Dieckmann et al, 1993, 1999, 2002; Daugaard et al, 1996; Harland et al, 1998).
With regards to treatment, low-risk patients benefit essentially of surgery and induction chemotherapy to improve response rates while high-risk patients undergo a systematic induction chemotherapy before surgery, high-dose chemotherapy and retinoic acid-based maintenance treatments (Matthay et al, 1999; Valteau-Couanet et al, 2005).
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We show that the fractal structure of this surface undergoes a systematic reorganization during substorm phases.
The design and operation of rotary kilns have undergone a systematic evolution since the days of the ancient Egyptians.
In the last ten years, random metric theory and its applications in the theory of conditional risk measures have undergone a systematic and deep development [5 13].
However, the magnitude of the D-variations is small and reverses in direction near the dip equator, undergoing a systematic increase with increasing latitude.
Consequently, the present approach has undergone a systematic study to examine its anticipated validity in real practice and to optimize its performance at various varying operating conditions.
In the last 10 years, the theory of RN modules together with their random conjugate spaces have undergone a systematic and deep development [3 9], in particular the random reflexivity based on the theory of random conjugate spaces and the study of semigroups of random linear operators have also obtained some substantial advances in [6, 8, 10 12].
Of the 38.7% patients who underwent a systematic LND, 122 (30.7%) and 38 (9.6%) were staged as N0 and N1+, respectively.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com