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This is due to stimulation of Jak1 by IL-9, resulting in activation of STATs 1, 3, and 5. Th9 cells undergo a maturation program similar to Th2 cells, with IL-4 inducing STAT6 activation and produce the Th2 cytokines IL-9 and IL-10, but, unlike Th2 cells, they require TGF β for maturation [ 13, 48].
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Notably, although resting-zone stem cells clearly belong to the chondrocyte lineage, Mizuhashi and colleagues found that they express a comparable set of stem-cell markers and undergo a maturation process similar to that of bone-marrow stem cells.
These results suggest that TDP-43 pathology spreads via the connectome of the injection site to different neuronal populations which then undergo a maturation process from diffuse granular deposits to condensed compact inclusions.
Upon antigenic stimulation, immature DC undergo a maturation process which leads to a number of phenotypical and functional changes.
After phagocytosis, phagosomes normally undergo a maturation process that culminates in lysosomal fusion and microbe killing [37].
Autophagosomes undergo a maturation process in animal cells, which involves the recruitment of the SNARE protein syntaxin 17 [ 22– 22].
As respiratory control and associated reflexes undergo a maturation process, it is expected that the cough would likewise undergo developmental stages as well.
Vacuolar Iigp1 accumulations undergo a maturation-like process accompanied by vesiculation of the parasitophorous vacuole membrane [33].
Fasoli, M. et al. The grapevine expression atlas reveals a deep transcriptome shift driving the entire plant into a maturation program.
"But we think of the format as an alternative cinematic art form that is undergoing a maturation process," Mr. Katz said.
We're undergoing a maturation phase here.
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