The present case is in line with this study and supports the notion that HTN and its associated changes and sequelae are not only an important substrate but also a hitherto underestimated therapeutic target for persistent AF.
The results of this study showed that women tended to mostly overestimate the target, whereas men tended to both overestimate and underestimate the target, resulting in a lower constant error and a higher variability in men compared to women.
However, the analysis of the direction of error (constant error) showed a significant difference between the sexes, as women tended to mostly overestimate the target, whereas men tended to both overestimate and underestimate the target (p-value ≤ 0.01, observed power = 0.79).
As the rate control underestimates the target rate, the required bits to match the target bitrate are added to the bitstream.
Based on previous findings (Mateeff & Gourevich, 1983), it was hypothesized that participants would show a foveal bias: underestimating perceived target locations, with the degree of error increasing with the true eccentricity of the target.
To rub more salt into the textual wound, the "esoteric" Professor Middleton refers to academic concepts like "linguistic signification" to the Barney Fife-like befuddlement of those around her. Either Ms. Brevoort deeply underestimates her target audience, or the characters are all half-wits.
Don't underestimate your target audience.
Given all the efforts made by some authors to convince the scientific community of the use of GM-CSF, it is challenging to read the conclusion of this present paper given that GM-CSF has been previously underestimated as a target for therapeutic intervention in many bacterial infections and inflammatory disorders associated with the production of IL-1β.
Our whole-exome sequencing result only covered a fraction of the genome and likely underestimated the off-target effects in human 3PN zygotes.
This study in a working population may have underestimated the extent of target organ disease in the general population because people with debilitating effects from target organ damage would be under represented in the working group.
