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At 4 h p.i., the 2T4k+VB fit underestimated activity concentrations compared to measured TAC (VOIViable) by 14.7 ± 7.7%, while the 2T3k+VB fit overestimated by 10.2 ± 7.4%.
In practice, the process of creating and maintaining a SAD tends to be a low-priority or underestimated activity in many projects (due to budget constraints, tight schedules, or pressures on developing features, among other reasons).
Unfortunately, low solubility affects bioassays by causing underestimated activity, reduced HTS-hit rates, variable data, inaccurate SAR, discrepancies between enzyme and cell assays and inaccurate in vitro ADME Tox testing.
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Current generation ToF scanners can consistently reconstruct Y activity concentrations, but they underestimate activity concentrations in small structures (≤37 mm diameter) within a warm background due to partial volume effects and constraints of the reconstruction algorithm.
However, midwives also seemed to underestimate activity when shifts were very busy and should have been categorised as escalation level 4 (red) where they were categorised as level 3 (amber).
Previous research suggests that removal of the device for water-based activities should not underestimate activities such as swimming due to the low levels of such activities such among Pakistani and Bangladeshi women in the UK [ 13].
We also found that the non-dicoumarol-inhibitable activity in the DT-diaphorase assay underestimated B5R activity, especially in cell lines with high DT-diaphorase activity.
For scans performed with cold water background (no activity), the reconstructions with TEW scatter correction underestimated the activity in small objects and overestimated it in large objects.
Also, as stated in a review by Shephard et al. (2003), responses from self-reported questionnaire can often be influenced by social desirability, resulting in overestimated physical activity levels and underestimated sedentary activities such as time spent watching television [ 31].
Therefore, we may have underestimated the activity levels for job types that have experienced reductions in activity within the job class.
However, livestock raising is also a very important yet underestimated economic activity in western Burkina Faso.
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