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Although the nomogram predicted probabilities were lower than the actual probabilities, dichotomous outcomes showed only a few false negatives in both sets and high negative predictive values in the training set (88.0%; 95% CI, 0.79 to 0.95) and validation set (77.8%; 95% CI, 0.60 to 0.87), which implies that the cutoff value was still effective under underestimated conditions.
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In general, many authors conclude that psychological disorders such as anxiety and depression are likely to be under-diagnosed, underestimated and certainly under-treated in patients with CKD, including those with ADPKD [ 10, 17, 22– 22].
Women are under-represented and underestimated.
Such genetic heterogeneity may reflect different tumour clones and its role is believed to be under-recognized and underestimated in neuroblastoma biology [29].
First, it is possible that female liver cancer has been systematically under-detected and underestimated over earlier cancer registration periods, and that the increase in the recent period (1998 2006) may primarily reflect improved registration in women.
Longer branch lengths were more underestimated under a uniform prior than under an exponential prior, consistent with their lower probability under a uniform than exponential prior.
As a result, the number of patients who have developed chronic neuro-cognitive dysfunction following malaria has been underestimated and under-reported.
But with the exception of the town of St-Tropez, this low-key département remains understated, under-visited and frequently underestimated.
The fashion industry is secretly sick of being underestimated and under-intellectualized.
This means that patients' psychological needs may go unrecognized, underestimated and under-treated.
Therefore, the incidence of small-cell carcinoma and the clinical impact of this subtype of prostate cancer in elderly men is likely underestimated and under-reported.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com