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This is direct evidence that expression of complex genes is under tighter regulation than the rest of the genome.
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We reasoned that nit-6 might also be under tight regulation in N. crassa and would be useful for experiments requiring regulated protein expression.
As ANG-2 is an antagonist of ANG-1/Tie-2 itsexpression iss expression is under tight regulation.
The osmolarity of the bodily fluids are under tight regulation since sustaining isosmolar conditions is essential for the normal functioning of the cells.
However, the ubiquitin ligase activity of CHIP on p53 is likely under tight regulation but the mechanics behind this control remain unclear.
It has been reported that even with nuclear β-catenin elevated, transcription of target genes is still under tight regulation by APC (57).
It is proposed that this interaction is under tight regulation; however the signaling/regulatory components of Dg-Dys complex remain elusive.
Cdc42 of the Rho GTPase family is an intracellular signal transducer that cycles between an inactive GDP-bound form and an active GTP-bound form under tight regulation [11].
In this case, miR-132 regulates the translation of transcriptional co-repressor methyl CpG binding protein 2 (MeCP2), the levels of which are under tight regulation in the brain as both increases and decreases in it expression have been shown to result in neurodevelopmental defects.
Cell proliferation is a complex process under tight regulation.
Under non-stress conditions, Nrf2 is under tight regulation by the ubiquitin proteasome system (UPS).
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