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The excavation by the shield tunnel changes the stress distribution of the ground under the spread foundation.
When the ground loss ratio increased, the Mohr circle of ground stress under the spread foundation moved to the left, closer to the ground failure line.
The greater the load, the higher the stress concentration; thus, the stress distribution in the ground under the spread foundation is the main factor affecting the stability of the ground around the tunnel and the spread foundation.
Thus, shield tunnel excavation close to the spread foundation changes the ground stress state and can lead to the instability and failure in the ground under the spread foundation.
The results indicated that hepatocytes exhibited lower 3H-thymidine uptake under the round morphology on the higher galactose density and higher 3H-thymidine uptake under the spread morphology on the lower galactose density.
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