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Under the Overlapping model, T appears as a critical parameter (Additional file 6: Table S6), and the most likely values estimated for T are very consistent among the three HLA loci (in generations: 1,213 for HLA−A, 1,193 for HLA−B and 1,363 for HLA−DRB1, Fig. 4c), corresponding to about 24,000-36,000 years depending on the generation time considered 20-30 yearss). 20-30 years
RMSEP charts of the parameters under the Overlapping model.
The posterior distribution of these parameters was estimated with 6 PLS under the Overlapping model, which resulted in relatively high p-values (>29 %).
According to the RMSEP charts (Additional file 6: Table S6), two locus-related parameters, i.e. the initial number of lineages (A) and the selection coefficient (s), affect most statistics under the Overlapping model.
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They also "decisively" [ 47] favor the Overlapping model over the Pincer model.
For the overlapping region, we calculated the transition-probability matrixes (based on the overlapping models in equations 5 and 6).
The overlapping models can be used singly or in concert to predict the functional site.
If performed correctly, you should see the two overlapping models.
In Appendix C I show that the results also carry over to a dynamic overlapping model with an infinite horizon.
For the non-overlapping regions, we calculated the transition-probability matrixes based on the non-overlapping model in equation 1.
Good preservation of these individual pedogenic processes is shown to be a soil memory under the overlapping press of Holocene pedogenesis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com