Under these conditions, the encapsulation efficiency was around 76.85% and the polydispersity index was around 0.281, indicating a good dimensional distribution.
GelMA is produced by the chemical functionalization of gelatin and can be covalently crosslinked under gentle conditions, allowing the encapsulation of chondrocytes with high viability24.
A small GroEL-binding tag made it possible to perform all steps of the encapsulation under near physiological conditions while retaining the native conformation of the target protein.
As a consequence, a large number of empty droplets are produced under conditions that prevent the encapsulation of two cells in the same droplet.
The encapsulation capacity, microstructure, in vitro releasing property under simulated gastric (SGF) and intestinal fluid (SIF) were measured.
Breaking the encapsulation of joins serves two purposes.
For the neighborhood, the encapsulation project is not entirely a defeat.
The group is also developing other drugs based on the encapsulation method.
Fig. 7 The encapsulation process.
The encapsulation efficiency reached 95%.
