Sentence examples for under the cleavage from inspiring English sources

Therefore, under the cleavage assay conditions (pH 7.3), only ∼50% of the phosphonate moiety is dianionic, although modeling suggests that this form is required for optimal binding through magnesium ion chelation.

Under these conditions the cleavage of sites depends on site accessibility thus representing the level of chromatin compactness of the tested locus.

Endogenous or environmental particulate dangers trigger innate immunity through assembly of the Nlrp3 inflammasome, an intracellular molecular platform which under activation allows the cleavage of the potent pro-inflammatory cytokine interleukin-1 β (IL-1 β).

Under these conditions, the cleavage products of XBP1-BSL NZ co-migrated at the same position as the input RNA unless the sample was heat-denatured (Fig 4E and F, compare lanes 2 and 4), indicating that XBP1-BSL NZ indeed failed to eject the intron.

Under the operative conditions, the cleavage of the olefinic double bond is not observed.

After 4 h incubation under the same conditions, the cleavage of MTT to formazan by metabolically active cells was quantified by scanning the plates at 540 nm using a Multiskan EX (Finland) apparatus.

Under the H1 promoter, the cleavage guidance (antisense) strand could be positioned at the 5' or 3' halves of the stem in the relevant constructs without any sequence restrictions.

Samples were subsequently digested by DNase I under "limiting conditions" and the cleavage products separated by denaturing polyacrylamide gel electrophoresis.

The second center is oxidized preferentially in alkaline media at higher potentials under the hydrolytic cleavage of diisopropylamine and formation of corresponding aldehydes.

Careful choice of the phosphate protecting group was essential, as the traditional dibenzyl phosphate protection failed to be cleanly removed under the peptide cleavage conditions.

APP can be alternatively processed by α-secretase within the A β region and generate a longer C-terminal fragment under the first cleavage.