For those cases supporting positive selection, the sites under selective pressure were identified from a high posterior probability to belong to the classes with dN/dS>1.
In order to select the sites under selective pressure, we assumed a p value of ≤0.1 or a posterior probability of ≥0.9 [19].
Several genes involved in determining skin color have been under selective pressure in Europeans and East Asians.
And that, Dr. Wrangham said, suggests the males were no longer under selective pressure to get bigger themselves.
Under selective pressure, amplified oncogenes are overexpressed, while coamplified passenger genes may be silenced epigenetically.
By contrast, the versions of the gene possessed by monkeys, dogs, cats and cows show no particular sign of being under selective pressure.
The genes under selective pressure found in one continent-based population or race are mostly different from those that occur in the others.
Our results suggest that PvDBPII of Korean P. vivax isolates display a limited genetic polymorphism and are under selective pressure.
Hence, new combinational therapies must be developed with the understanding that compensatory mechanisms evolve under selective pressure.
This independence suggests that a small patch of chromosomal region around the HWC2 locus might have been under selective pressure.
It is also possible to improve the performance by culturing microorganisms under selective pressure for enhanced power production [30, 72].
