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Substitutions critical for expanding substrate profile or increasing hydrolytic activities are efficiently selected under selection pressure of β-lactam use.
Hosts are under selection pressure to evolve resistance against pathogens whereas pathogens are under selection pressure to evolve counter-resistance against the resistance mechanism of their host.
Viruses might therefore be under selection pressure to adapt to the monomorphic proteasome and TAP.
Upon re-cultivation of this orange transformants under selection pressure, white colonies homozygote for disrupted crtI were obtained.
Will robotic backbones become progressively stiffer in successive generations, thus corroborating the author's hypothesis that vertebral columns evolved from notochords under selection pressure for enhanced feeding?
Once herbicide resistance genes move into weeds, their frequency within local weed populations will increase under selection pressure by the corresponding herbicide.
NLRs are highly variable in sequence, suggesting that they are under selection pressure, but also that they may be manipulated to generate proteins with new recognition specificities.
In turn, symbioses could evolve from extra- to intracellular types under selection pressure for the most stable efficient nutritional intake.
In this way we estimated that on average 18% of the epitope precursors are under selection pressure in a host, i.e. are an actual epitope in that host.
Such loss is consistent with the fact that pseudogenes are no longer under selection pressure, with many becoming fragmented as compared to functional genes [3].
Subsequently, under selection pressure, the enzyme would lose its second acyl pocket Phe residue to obtain the substrate specificity of BChE in the higher vertebrates.
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