It was designed to work under normal, undisturbed operational conditions.
Thus, these deleted genes optimize essential systems, which are functional under normal growth conditions but become dysfunctional at conditions like polyQ intoxication.
One possible objection to our conclusion that AOX does not increase lifespan despite diminishing mtROS production would be that the enzyme may not be functional under normal physiological conditions.
The transcriptome atlas revealed notable differential expression in either transcript abundance or in expression patterns under normal growth conditions, which indicated wide functional divergence in this family.
Taken together, the relatively mild phenotypes of α1, α2 and α11 mutant mice suggest that, under normal physiological conditions, there is a functional redundancy between the individual collagen receptors.
Under normal conditions, MAS1 produces a functional complex with the other A-II receptors, AT1R and AT2R, to maintain vascular homeostasis.
Moreover, the highly similar fluorescent spot patterns in gels separating proteins from the striatum and the hippocampus indicate that both of these brain structures may express essentially the same major proteins on postnatal day (PD) 11, thereby showing their functional importance under normal conditions of BGS.
If someone believes that the law f(X)=Y holds, then she believes that this functional relation holds under normal conditions N, which means in terms of Spohn's ranking functions that the law f(X)=Y is believed with rank zero, i.e., it is true in all normal worlds of a ranked world model.
Under normal physiologic conditions, chondrocytes maintain an equilibrium between anabolic and catabolic activities that is necessary for preservation of the structural and functional integrity of the tissue.
Interestingly, in Arabidopsis, according to the experimental results of Dong et al. [ 45], more than half of the members in subgroup II b showed similar preferential expression in the root tissue under normal conditions, which indicated the conserved functional role of subgroup II b in root development between the two species.
Under normal market conditions that makes sense.
